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Photoreactivity of ruthenium complexes with biomolecules

F. Alary, M. Boggio-Pasqua, J.-L. Heully ; collaboration : P. Vicendo (LIMRCP, Toulouse).

This project is based on a joint experimental and theoretical study of the photoreactivity of ruthenium complexes towards DNA or metalloproteins. From a theoretical point of view, it is meant to decipher, on a molecular level, the interactions involved between certain molecules and their biological targets. This may help to design more selective or more effective compounds.

This project has led to 3 publications :

Inorg. Chem. 2007, 46, 3154 link

Inorg. Chem. 2008, 47, 5259 link

Chem. Eur. J. 2009, 15, 2759 link